iS Clinical Super Serum Advance+ Review | SkinSourcer
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The Shelf · Peptide Skincare for Playing the Long Game

iS Clinical Super Serum Advance+
No. 10 in Edit 008

iS Clinical Super Serum Advance+

Serums USA Approx. $177

Time-released L-ascorbic acid with a copper tripeptide, arbutin and hyaluronic acid, from the clinic brand that already has five products on The Shelf. Super Serum is the one for tone: the vitamin C and the arbutin are aimed at marks, and the peptide is there for everything else.

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Why we like the Super Serum Advance+

  • L-ascorbic acid second on the list
  • Arbutin and a copper peptide
  • Fragrance-free
  • The clinic brand's tone specialist
Texture
A watery serum
Key ingredients
Time-released L-ascorbic acid · Copper tripeptide · Arbutin · Hyaluronic acid
Fragrance
Fragrance-free
Skin type
Mature
Best for
Uneven tone · Morning use · Skin recovering from sun
Works on
Dark spots · Fine lines · Pigmentation
Made in
USA
Where to buy
Dermstore
Price when checked
$177 on 2026-09-09
Listing checked
2026-09-06

Our verdict on the iS Clinical Super Serum Advance+

The clinic brand's tone serum.

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Where the Super Serum Advance+ sits on The Shelf

Peptide Skincare for Playing the Long Game Edit 008 · THE PEPTIDE EDIT Peptide Skincare for Playing the Long Game Twelve formulas between twenty one and four hundred and seventy five dollars, and what the extra money buys.

The rest of Peptide Skincare for Playing the Long Game

The Ordinary Multi-Peptide + Copper Peptides 1% The Ordinary Multi-Peptide + Copper Peptides 1% COSRX 6X Peptide Collagen Skin Booster Toner Serum COSRX 6X Peptide Collagen Skin Booster Toner Serum Naturium Multi-Peptide Advanced Serum Naturium Multi-Peptide Advanced Serum Medik8 Liquid Peptides Medik8 Liquid Peptides Allies of Skin Peptides & Antioxidants Advanced Firming Daily Treatment Allies of Skin Peptides & Antioxidants Advanced Firming Daily Treatment Olay Regenerist Micro-Sculpting Cream Olay Regenerist Micro-Sculpting Cream Drunk Elephant Protini Polypeptide Cream Drunk Elephant Protini Polypeptide Cream Revision Skincare Revox Line Relaxer Revision Skincare Revox Line Relaxer Medik8 Niacinamide Peptides Medik8 Niacinamide Peptides Noble Panacea The Absolute Peptide 8 Night Serum Noble Panacea The Absolute Peptide 8 Night Serum Eighth Day The Regenerative Serum Eighth Day The Regenerative Serum

Reviewed 2026-09-06. iS Clinical Super Serum Advance+ appears in Peptide Skincare for Playing the Long Game. Every product on The Shelf is listed in the product index.